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上海酶联文献:Methionine and Its Hydroxyl Analogues Improve Stem Cell Activity To Eliminate Deoxynivalenol-Induced Intestinal Injury by Reactivating Wnt/β-Catenin Signaling

Jia-yi Zhou,† Zhe Wang,§ Sai-wu Zhang,† Hua-lin Lin,† Chun-qi Gao,†,‡ Jiang-chao Zhao,# Chengbo Yang,⊥ and Xiu-qi Wang*,†

†College of Animal Science, South China Agricultural University/Guangdong Provincial Key Laboratory of Animal Nutrition Control/National Engineering Research Center for Breeding Swine Industry, Guangzhou, Guangdong 510642, China

‡Integrative Microbiology Research Centre, South China Agricultural University, Guangzhou, Guangdong 510642, China

§College of Letters & Science, University of Wisconsin-Madison, Madison, Wisconsin 53706, United States

#Department of Animal Science, University of Arkansas, Fayetteville, Arkansas 72701, United States

⊥Department of animal science, Faculty of Agricultural and Food Sciences, University of Manitoba, Winnipeg, Manitoba R3T 2N2, Canada




Figure 1. Met and HMB increase the growth of mice exposed to DON. (A)Experimental procedure. A total of 72 male mice with similar body weights were assigned randomly to six groups (CON, Met, HMB, DON, D + M, and D + H). The CON group mice were treated orally with physiological saline, the Met group mice were treated orally with Met, the HMB group mice were treated orally with HMB, the DON group mice were treated orally with DON on days


4−8, the D + M group mice were treated orally with Met on days 1− 11 and DON on days 4−8, and the D + H group mice were treated orally with HMB on days 1−11 and DON on days 4−8. (B−D) Average daily feed intake (ADFI) (B), average daily water intake(ADWI) (C), and average daily gain (ADG) (D) were monitored during the experiment. The data are the mean ± SEM (n = 12).


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