产品货号 : mlR11822
英文名称 : CSAD
中文名称 : 半胱氨酸亚磺酸脱羧酶抗体
别 名 : CSAD; CSAD_HUMAN; CSD; Cysteine sulfinic acid decarboxylase; Cysteine-sulfinate decarboxylase; Sulfinoalanine decarboxylase.
研究领域 : 肿瘤 神经生物学 信号转导 新陈代谢
抗体来源 : Rabbit
克隆类型 : Polyclonal
交叉反应 : Human, Mouse, Rat, Dog, Horse,
产品应用 : WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 : 55kDa
细胞定位 : 细胞浆 细胞外基质
性 状 : Lyophilized or Liquid
浓 度 : 1mg/ml
免 疫 原 : KLH conjugated synthetic peptide derived from human CSAD:401-493/493
亚 型 : IgG
纯化方法 : affinity purified by Protein A
储 存 液 : 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 : Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed : PubMed
产品介绍 : CSAD is a 493 amino acid protein that exists as a homodimer and belongs to the group II decarboxylase family. CSAD catalyzes the conversion of 3-sulfino-L-alanine to hypotaurine and carbon dioxide, binds pyridoxal phosphate as a cofactor and undergoes alternative splicing to produce three isoforms. The gene encoding CSAD maps to human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5% of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and trisomy 12p, which causes facial developmental defects and seizure disorders.
Subunit:
Homodimer.
Similarity:
Belongs to the group II decarboxylase family.
SWISS:
Q9Y600
Gene ID:
51380
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品图片