产品货号 :  mlR19487

英文名称 :  NT5C1B/RDH14

中文名称 :  胞浆5'核苷酸酶1B抗体

别    名 :  5' nucleotidase cytosolic IB; 5' nucleotidase cytosolic IB isoform CRA_b; 5NT1B_HUMAN; AIRP; Autoimmune infertility-related protein; CN IB; cN-IB; cN1B; CNIB; Cytosolic 5' nucleotidase 1B; Cytosolic 5' nucleotidase IB; Cytosolic 5'-nucleotidase 1B; Cytosolic 5'-nucleotidase IB; MGC26640; Nt5c1b 5' nucleotidase cytosolic IB; NT5C1B; Nt5c1b protein; Nucleotidase 5 prime cytosolic IB; Rdh14.  

研究领域 :  细胞生物  表观遗传学  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应 :  Human, Mouse, Rat,

产品应用 :  ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  69kDa

细胞定位 :  细胞浆

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human NT5C1B:1-100/610

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍 :   This locus represents naturally occurring read-through transcription between the neighboring NT5C1B (5'-nucleotidase, cytosolic IB) and RDH14 (retinol dehydrogenase 14) genes on chromosome 2. Alternative splicing results in multiple transcript variants, one of which encodes a fusion protein that shares sequence identity with the products of each individual gene. [provided by RefSeq, Nov 2010]

Function:

Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides. Helps to regulate adenosine levels.

Subcellular Location:

Cytoplasm.

Tissue Specificity:

Highly expressed in testis, placenta and pancreas. Detected at lower levels in heart, kidney, liver and lung.

Similarity:

Belongs to the 5'-nucleotidase type 3 family.

SWISS:

Q96P26

Gene ID:

100526794

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.