产品货号 :  mlR18842

英文名称 :  RQCD1

中文名称 :  细胞分化蛋白质RCD1抗体

别    名 :  CAF40; CCR4-NOT transcription complex subunit 9; Cell differentiation protein RCD1 homolog; CNOT9; CT129; Homo sapiens protein involved in sexual development complete cds; Rcd 1; Rcd-1; Rcd1 (required for cell differentiation, S.pombe) homolog 1; RCD1; RCD1 required for cell differentiation1 homolog; RCD1 required for cell differentiation1 homolog (S. pombe); RCD1+; RCD1_HUMAN; rqcd1.  

研究领域 :  细胞生物  转录调节因子  表观遗传学  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应 :  Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Zebrafish, Sheep,

产品应用 :  ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  33kDa

细胞定位 :  细胞浆

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human RQCD1:81-180/299

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍 :   This gene encodes a member of the highly conserved RCD1 protein family. The encoded protein is a transcriptional cofactor and a core protein of the CCR4-NOT complex. It may be involved in signal transduction as well as retinoic acid-regulated cell differentiation and development. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Oct 2012] 

Function:

Transcription factor that down-regulates MYB- and JUN-dependent transcription. May play a role in cell differentiation (By similarity). Can bind oligonucleotides, such as poly-G, poly-C or poly-T (in vitro), but the physiological relevance of this is not certain. Does not bind poly-A. 

Subcellular Location:

Nucleus. Cytoplasm > P-body. NANOS2 promotes its localization to P-body.

Tissue Specificity:

Detected in spleen, thymus, prostate, testis, ovary and intestine. 

Similarity:

Belongs to the RCD1 family. 

SWISS:

Q92600

Gene ID:

9125

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.