产品货号 :  mlR13497

英文名称 :  GPAT2

中文名称 :  3-磷酸甘油酰基转移酶2抗体

别    名 :  Glycerol-3-phosphate acyltransferase 2; GPAT-2; GPAT2; GPAT2_HUMAN; mitochondrial; xGPAT1.  

研究领域 :  细胞生物  信号转导  转运蛋白  新陈代谢  线粒体  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应 :   Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,

产品应用 :  WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  88kDa

细胞定位 :  细胞浆 细胞膜 线粒体

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human GPAT2:51-150/795

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍 :   GPAT2 is an 801 amino acid mitochondrial multi-pass membrane protein belonging to the GPAT/DAPAT family. GPAT2 is highly expressed in testis with lower levels in heart, liver, kidney, spleen and adipose cells. Inhibited by N-ethylmaleimide (NEM), GPAT2 esterifies an acyl-group from acyl-ACP to the sn-1 position of glycerol-3-phosphate, an essential step in glycerolipid biosynthesis. GPAT2 contain a HXXXXD motif, which is critical for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate. Three isoforms of GPAT2 exist due to alternative splicing events.

Function:

Esterifies acyl-group from acyl-ACP to the sn-1 position of glycerol-3-phosphate, an essential step in glycerolipid biosynthesis.

Subcellular Location:

Mitochondrion outer membrane.

Similarity:

Belongs to the GPAT/DAPAT family.

SWISS:

Q6NUI2

Gene ID:

150763

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

产品图片