产品货号 :  mlR6714

英文名称 :  UGCGL2

中文名称 :  二磷酸葡萄糖神经酰胺葡萄糖基转移酶2抗体

别  名 :  HUGT2; UGCGL 2; Moderately similar to UDP glucose:glycoprotein glucosyltransferase; UDP Glc glycoprotein glucosyltransferase 2; UDP glucose ceramide glucosyltransferase like 1; UDP glucose ceramide glucosyltransferase like 2; UDP glucose glycoprotein glucosyltransferase 2; UGT2; UGGG2_HUMAN.  

研究领域 :  细胞生物  信号转导  激酶和磷酸酶  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应 :   Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Sheep,

产品应用 :  WB=1:500-2000 ELISA=1:500-1000  

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  172kDa

细胞定位 :  细胞浆

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human UGCGL2:201-300/1516

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍background:

UDP-glucose:glycoprotein glucosyltransferase (UGT) is a soluble protein of the endoplasmic reticulum (ER) that selectively reglucosylates unfolded glycoproteins, thus providing quality control for protein transport out of the ER.[supplied by OMIM, Oct 2009]

Function:

Recognizes glycoproteins with minor folding defects. Reglucosylates single N-glycans near the misfolded part of the protein, thus providing quality control for protein folding in the endoplasmic reticulum. Reglucosylated proteins are recognized by calreticulin for recycling to the endoplasmic reticulum and refolding or degradation.

Subcellular Location:

Endoplasmic reticulum lumen. Endoplasmic reticulum-Golgi intermediate compartment.

Tissue Specificity:

Higher levels in kidney, pancreas, heart, and skeletal muscle.

Similarity:

Belongs to the glycosyltransferase 8 family.

SWISS:

Q9NYU1

Gene ID:

55757

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

产品图片