产品货号 :  mlR6249

英文名称 :  LCMT1

中文名称 :  亮氨酸羧基甲基转移酶1抗体

别    名 :  CGI 68; LCMT; LCMT1; LCMT1_HUMAN; Leucine carboxyl methyltransferase 1; PPMT1; Protein leucine O methyltransferase; Protein-leucine O-methyltransferase.  

研究领域 :  肿瘤  信号转导  激酶和磷酸酶  表观遗传学  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应 :   Human, Mouse, Rat,

产品应用 :  WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 （石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  38kDa

细胞定位 :  细胞核 细胞浆

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human LCMT1:45-150/334

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍background:

LCMT1 catalyzes the methylation of the carboxyl group of the C-terminal leucine residue (leu309) of the catalytic subunit of protein phosphatase-2A (PPP2CA; MIM 176915)

Function:

LCMT1, or leucine carboxyl methyltransferase 1, methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits (PPP2CA) to form alpha-leucine ester residues.

Similarity:

Belongs to the methyltransferase superfamily. LCMT family.

SWISS:

Q9UIC8

Gene ID:

51451

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

产品图片