产品货号 :  mlR16819

英文名称 :  KRT24 

中文名称 :  细胞角蛋白24抗体

别    名 :  CK 24; CK24; Cytokeratin 24; FLJ20261; K24; KA24; K1C24_HUMAN; Keratin 24; Keratin, type I cytoskeletal 24; KRT24; MGC138169; MGC138173; Type I keratin 24.   

研究领域 :  肿瘤  细胞生物  免疫学  信号转导  细胞骨架  

抗体来源 :  Rabbit 

克隆类型 :  Polyclonal 

交叉反应 :   Human, Mouse, Rat, Pig, Cow, Sheep, 

产品应用 :  ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user. 

分 子 量 :  55kDa

细胞定位 :  细胞浆 细胞外基质 分泌型蛋白

性    状 :  Lyophilized or Liquid 

浓    度 :  1mg/ml 

免 疫 原 :  KLH conjugated synthetic peptide derived from human KRT24:101-200/525 

亚    型 :  IgG 

纯化方法 :  affinity purified by Protein A 

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. 

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 

PubMed :  PubMed 

产品介绍background:

This gene encodes a member of the type I (acidic) keratin family, which belongs to the superfamily of intermediate filament (IF) proteins. Keratins are heteropolymeric structural proteins which form the intermediate filament. These filaments, along with actin microfilaments and microtubules, compose the cytoskeleton of epithelial cells. The type I keratin genes are clustered in a region of chromosome 17q12-q21. [provided by RefSeq, Jun 2009]

Function:

KRT24 is a member of the type I (acidic) keratin family, which belongs to the superfamily of intermediate filament (IF) proteins. Keratins are heteropolymeric structural proteins which form the intermediate filament. These filaments, along with actin microfilaments and microtubules, comprise the cytoskeleton of epithelial cells. KRT24 is highly expressed in keratinocytes, placenta, colon and spleen, and has been found to be up-regulated in the mucosa of patients suffering of colorectal cancer. 

Subcellular Location:

Intermediate filament; keratin

Similarity:

Belongs to the intermediate filament family.

SWISS:

Q2M2I5 

Gene ID:

192666

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.