产品货号 :  mlR9965

英文名称 :  PDCL3

中文名称 :  光导蛋白样蛋白PDCL3抗体

别    名 :  HTPHLP; IAP associated factor VIAF1; MGC3062; PDCL 3; Pdcl3; PDCL3_HUMAN; PHLP2A; PHLP3; Phosducin like 3; Phosducin like protein 3; Phosducin-like protein 3; PhPL3; VIAF 1; VIAF; VIAF-1; VIAF1; Viral IAP associated factor 1; Viral IAP-associated factor 1.  

研究领域 :  细胞生物  细胞凋亡  G蛋白偶联受体  G蛋白信号  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应 :  Human, Mouse, Rat, Dog, Rabbit, Zebrafish,

产品应用 :  IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  25kDa

细胞定位 :  细胞浆

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human PDCL3:1-100/239

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍 :  This gene encodes a member of the phosducin-like protein family and is a putative modulator of heterotrimeric G proteins. The protein shares extensive amino acid sequence homology with phosducin. Members of the phosducin-like protein family have been shown to bind to the beta-gamma subunits of G proteins. [provided by RefSeq, Jul 2008]

Function:

Modulates the activation of caspases during apoptosis. Is a substrate for Orgyia pseudotsugata multicapsid polyhedrosis virus (OpMNPV) IAP-mediated ubiquitination.

Subcellular Location:

Cytoplasm.

Tissue Specificity:

Expressed in all tissues examined including spleen, thymus, prostate, testis, ovary, small intestine and colon.

Similarity:

Belongs to the phosducin family.

SWISS:

Q9H2J4

Gene ID:

79031

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.