产品货号 :  mlR9963

英文名称 :  PDCD2

中文名称 :  凋亡相关蛋白2抗体

别    名 :  MGC12347; OTTHUMP00000017702; PDCD 2; Pdcd2; PDCD2 protein; PDCD2_HUMAN; Programmed cell death 2; Programmed cell death protein 2; RP 8; RP8; Rp8 homolog; Zinc finger MYND domain containing protein 7; Zinc finger MYND domain-containing protein 7; Zinc finger protein Rp 8; Zinc finger protein Rp-8; Zinc finger protein Rp8; ZMYND 7; ZMYND7.  

研究领域 :  肿瘤  细胞生物  细胞凋亡  细胞周期蛋白  转录调节因子  b-淋巴细胞  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应 :  Human, Mouse, Rat, Sheep,

产品应用 :  ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  39kDa

细胞定位 :  细胞核

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human PDCD2:111-310/344

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍 :  This gene encodes a nuclear protein expressed in a variety of tissues. Expression of this gene has been shown to be repressed by B-cell CLL/lymphoma 6 (BCL6), a transcriptional repressor required for lymph node germinal center development, suggesting that BCL6 regulates apoptosis by its effects on this protein. Alternative splicing results in multiple transcript variants and pseudogenes have been identified on chromosomes 9 and 12. [provided by RefSeq, Dec 2010]

Function:

May be a DNA-binding protein with a regulatory function. May play an important role in cell death and/or in regulation of cell proliferation.

Subcellular Location:

Nucleus.

Tissue Specificity:

Ubiquitous.

Similarity:

Contains 1 MYND-type zinc finger.

SWISS:

Q16342

Gene ID:

5134

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.