产品货号 :  mlR16838

英文名称 :  KRT85 

中文名称 :  细胞角蛋白85抗体 

别    名 :  Hair keratin K2.12; Hard keratin type II 5; Hb 5; HB5; hHb5; KRT85_HUMAN; K85; Keratin 85; keratin hair basic 5; Keratin type II cuticular Hb5; KRTHB5; Type II hair keratin Hb5; Type II keratin Kb25.  

研究领域 :  细胞生物  信号转导   

抗体来源 :  Rabbit 

克隆类型 :  Polyclonal

交叉反应 :   Human, Rat, Dog, Cow, Rabbit, Sheep, 

产品应用 :  WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user. 

分 子 量 :  56kDa 

细胞定位 :  细胞浆 细胞外基质 分泌型蛋白 

性    状 :  Lyophilized or Liquid 

浓    度 :  1mg/ml 

免 疫 原 :  KLH conjugated synthetic peptide derived from human KRT85:101-200/507 

亚    型 :  IgG 

纯化方法 :  affinity purified by Protein A 

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. 

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 

PubMed :  PubMed 

产品介绍background:

The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. [provided by RefSeq, Jul 2008]

Function:

KRT85 is a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. 

Subcellular Location:

Intermediate filament, Keratin filament 

Similarity:

Belongs to the intermediate filament family. 

SWISS:

P78386 

Gene ID:

3891 

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.