产品货号 :  mlR18214

英文名称 :  Leishmania Major Surface Protease

中文名称 :  利什曼原虫表面蛋白酶抗体

别    名 :  Cell surface protease; gp63; Leishmanolysin; Major surface glycoprotein; Major surface protease; MSP; GP63_LEIMA; Promastigote surface endopeptidase; Protein gp63; PSP.  

研究领域 :  免疫学  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应 :  Leishmania

产品应用 :  IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  51kDa

细胞定位 :  细胞膜

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from Leishmania Major Surface Protease:221-320/602

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍 :   The major surface metalloproteinase Gp63 plays an important role in the initial stages of Leishmania/macrophage interactions and the intracellular survival of the parasite. Leishmania is a protozoan of the genus of trypanosome, and the parasite responsible for the disease leishmaniasis.

Subcellular Location:

Cell Membrane

Post-translational modifications:

The phosphatidylinositol moiety of the GPI-anchor contains a fully saturated, unbranched 1-O-alkyl chain (mainly C24:0) and a mixture of fully saturated unbranched 2-O-acyl chains

Similarity:

Belongs to the peptidase M8 family.

Gene ID:

5653263

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.