产品货号 :  mlR9707

英文名称 :  Kazrin

中文名称 :  Kazrin蛋白抗体

别    名 :  HRIHFB2003; KAZ; Kazn; Kazrin; KAZRN_HUMAN; KIAA1026.  

研究领域细 :  胞生物  信号转导  细胞周期蛋白  细胞分化  细胞骨架  细胞外基质  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应 :   Human, Mouse, Rat, Dog, Pig, Cow,

产品应用 :  WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:50-200 （石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  86kDa

细胞定位 :  细胞浆

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human Kazrin:451-550/775

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍background :  

Component of the cornified envelope of keratinocytes. May be involved in the interplay between adherens junctions and desmosomes. The function in the nucleus is not known.

Function:

Component of the cornified envelope of keratinocytes.May be involved in the interplay between adherens junctions anddesmosomes. The function in the nucleus is not known.

Subunit:

Isoform 2, isoform 3 and isoform 4 interact with PPLN-terminus.

Subcellular Location:

Cytoplasm

Tissue Specificity:

Isoform 2, isoform 3 and isoform 4 are expressed in several cell lines including keratinocytes and bladder and epidermoid carcinoma (at protein level). Isoform 2, isoform 3 and isoform 4 are expressed in hair follicle and interfollicular epidermis (at protein level).

Similarity:

Belongs to the kazrin family.

Contains 3 SAM (sterile alpha motif) domains

SWISS:

Q674X7

Gene ID:

23254

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.