产品货号 :  mlR11402

英文名称 :  GCX1/C20orf100

中文名称 :  20号染色体开放阅读框100抗体

别    名 :  Chromosome 20 open reading frame 100; Chromosome 20 open reading frame 100; dJ1108D11.2; dJ495O3.1; GCX 1; GCX1; GCX-1; Granulosa cell HMG box protein 1; MGC15880; Weakly similar to NONHISTONE CHROMOSOMAL PROTEIN 6A [S.cerevisiae]; Weakly similar to NONHISTONE CHROMOSOMAL PROTEIN 6A [S.cerevisiae]; TOX2_HUMAN.  

研究领域 :  细胞生物  神经生物学  信号转导  表观遗传学  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应 :   Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,

产品应用 :  ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  52kDa

细胞定位 :  细胞核

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human GCX1/C20orf100:201-300/488

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍 :   GCX-1 is a 488 amino acid transcription activator that is restricted to expression in the hypothalamus, pituitary, ovary, testis and uterus. Human reproduction is controlled by the hypothalamic-pituitary gonadal axis (HPGA) that is laid down early in fetal development. This expression pattern in the HPGA suggests that this nuclear protein is likely related to specific events in reproduction, particularly in the female. GCX-1 contains a HMG-box domain, which is commonly found in proteins that function as intercellular regulators and transcriptional co-regulators, and are found to be involved in important events such as sex determination and in the regulation of T cell differentiation. There are two isoforms of GCX-1 which are produced as a result of alternative splicing events.

Function:

C20orf100 is a putative transcriptional activator involved in the hypothalamo-pituitary-gonadal system. It may regulate follicular development and other processes related to female reproduction.

Subcellular Location:

Nuclear

Similarity:

Contains 1 HMG box DNA-binding domain.

SWISS:

Q96NM4

Gene ID:

84969

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

产品图片