产品货号 :  mlR17733

英文名称 :  MOXD1

中文名称 :  单加氧酶X抗体

别    名 :  DBH like monooxygenase protein 1; DBH-like monooxygenase protein 1; dJ248E1.1; DKFZp564G202; Monooxygenase X; monooxygenase, DBH like 1; MOX; Moxd1; MOXD1_HUMAN; PRO5780.  

研究领域 :  细胞生物  细胞类型标志物  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应 :   Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,

产品应用 :  WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  68kDa

细胞定位 :  细胞浆

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human MOXD1:501-600/613

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍 :   MOXD1 is a 613 amino acid single-pass type I membrane protein of the Endoplasmic reticulum that belongs to the copper type II ascorbate-dependent monooxygenase family. Existing as two alternatively spliced isoforms, MOXD1 is expressed in adult spinal cord, adrenal gland, brain, testis, uterus, lung and kidney, as well as fetal liver and brain. MOXD1 is upregulated during replicative senescence in primary fibroblast and umbilical vein endothelial cell cultures, and uses two copper ions per subunit as a cofactor. MOXD1 contains one DOMON domain, undergoes post-translational N-glycosylation and is encoded by a gene that maps to human chromosome 6. Chromosome 6 contains 170 million base pairs, comprises nearly 6% of the human genome and is associated with early onset intestinal cancer, Porphyria cutanea tarda, Parkinson's disease and Stickler syndrome.

Subcellular Location:

Endoplasmic reticulum membrane.

Tissue Specificity:

Highly expressed in lung, kidney, brain and spinal cord.

Post-translational modifications:

N-glycosylated.

Similarity:

Belongs to the copper type II ascorbate-dependent monooxygenase family. Contains 1 DOMON domain.

SWISS:

Q6UVY6

Gene ID:

26002

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

产品图片