产品货号 : mlR23150
英文名称 : P2Y1
中文名称 : P2Y1受体抗体/嘌呤受体抗体
别 名 : ATP receptor; P2 purinoceptor subtype Y1; P2RY1; P2Y purinoceptor 1; P2Y1 purinoceptor; Platelet ADP receptor; Purinergic receptor; Purinergic receptor P2Y G protein coupled 1; Purinergic receptor P2Y1; P2RY1_HUMAN; P2Y1 purinoceptor.
研究领域 : 信号转导 转录调节因子 通道蛋白
抗体来源 : Rabbit
克隆类型 : Polyclonal
交叉反应 : Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep,
产品应用 : WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 : 41kDa
细胞定位 : 细胞膜
性 状 : Lyophilized or Liquid
浓 度 : 1mg/ml
免 疫 原 : KLH conjugated synthetic peptide derived from human P2Y1:301-373/373 <Cytoplasmic>
亚 型 : IgG
纯化方法 : affinity purified by Protein A
储 存 液 : 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 : Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed : PubMed
产品介绍 : The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor functions as a receptor for extracellular ATP and ADP. In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation. [provided by RefSeq, Jul 2008]
Function:
Receptor for extracellular adenine nucleotides such as ATP and ADP. In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation.
Subcellular Location:
Cell membrane; Multi-pass membrane protein.
Tissue Specificity:
Expressed in muscle, heart, liver, kidney, lung, brain, spleen, but not in testis.
Similarity:
Belongs to the G-protein coupled receptor 1 family.
SWISS:
P47900
Gene ID:
5028
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
P2Y1 receptor 为离子通道蛋白，一种受体配体开启的离子通道，介导细胞外核苷酸细胞间信号传导。
产品图片
