产品货号 : mlR21108
英文名称 : SFRS12/p18SRP
中文名称 : P18剪接调节蛋白抗体
别 名 : p18 splicing regulatory protein; p18SRP; P18SRP protein; Protein SFRS12IP1; Protein SREK1IP1; SFRS12 interacting protein 1; SFRS12-interacting protein 1; Splicing regulatory protein of 18 kDa; SR1IP_HUMAN; SREK1-interacting protein 1; SREK1IP1.
研究领域 : 细胞生物 表观遗传学
抗体来源 : Rabbit
克隆类型 : Polyclonal
交叉反应 : Human, Mouse, Cow, Horse, Sheep,
产品应用 : ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 : 18kDa
细胞定位 : 细胞核
性 状 : Lyophilized or Liquid
浓 度 : 1mg/ml
免 疫 原 : KLH conjugated synthetic peptide derived from human SFRS12/p18SRP:21-120/155
亚 型 : IgG
纯化方法 : affinity purified by Protein A
储 存 液 : Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
保存条件 : Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed : PubMed
产品介绍Function:
Participates in the regulation of alternative splicing by modulating the activity of other splice facors. Inhibits the splicing activity of SFRS1, SFRS2 and SFRS6. Augments the splicing activity of SFRS3.
Subunit:
Homodimer. Binds SFRS1, SFRS2, SFRS3 and SFRS6. Interacts with the spliceosome. Interacts with SREK1IP1.
Subcellular Location:
Nucleus.
Similarity:
Belongs to the splicing factor SR family.
Contains 1 RRM (RNA recognition motif) domain.
SWISS:
Q8N9Q2
Gene ID:
285672
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品图片