产品货号 :  mlR7630

英文名称 :  MTCH1

中文名称 :  细胞增殖诱导蛋白60（早老素相关蛋白）

别   名 :  Cell proliferation inducing protein 60; CGI-64; CGI64; Mitochondrial carrier homolog 1; Mitocondrial Carrier Homolog 1; MTCH 1; Mtch1; MTCH1_HUMAN; Presenilin Associated Protein; Presenilin-associated protein; PSAP.  

研究领域 :  细胞生物  神经生物学  信号转导  细胞凋亡  线粒体  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应 :   Human, Mouse, Rat, Dog, Pig, Horse,

产品应用 :  WB=1:500-2000 ELISA=1:500-1000  

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  42kDa

细胞定位 :  细胞浆 细胞膜 线粒体

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human MTCH1:151-250/389

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍 :   This gene encodes a member of the mitochondrial carrier family. The encoded protein is localized to the mitochondrion inner membrane and induces apoptosis independent of the proapoptotic proteins Bax and Bak. Pseudogenes on chromosomes 6 and 11 have been identified for this gene. Alternatively spliced transcript variants encoding multiple isoforms have been observed. [provided by RefSeq, Oct 2012]

Function:

Potential mitochondrial transporter. May play a role in apoptosis.

Subunit:

Interacts with PSEN1.

Subcellular Location:

Mitochondrion inner membrane; Multi-pass membrane protein (Potential).

Tissue Specificity:

Widely expressed with a predominant expression in brain.

Similarity:

Belongs to the mitochondrial carrier family.

Contains 2 Solcar repeats.

SWISS:

Q9NZJ7

Gene ID:

23787

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

产品图片 :