产品货号 :  mlR21088

英文名称 :  RABGGTA

中文名称 :  RABGGTA蛋白抗体

别    名 :  Geranylgeranyl transferase type 2 subunit alpha; Geranylgeranyl transferase type II subunit alpha; Geranylgeranyl transferase type-2 subunit alpha; PGTA_HUMAN; Protein prenyltransferase alpha subunit repeat containing 3; PTAR3; Rab geranyl geranyltransferase subunit alpha; Rab geranyl-geranyltransferase subunit alpha; Rab geranylgeranyltransferase alpha subunit; Rab geranylgeranyltransferase subunit alpha; Rab GG transferase alpha; Rab GGTase alpha; RABGGTA.  

研究领域 :  细胞生物  神经生物学  信号转导  G蛋白信号  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应  :  Human, Mouse, Rat, Pig,

产品应用 :  ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  65kDa

细胞定位 :  细胞浆

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human RABGGTA:131-330/567

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍background:

RABGGTA (Rab Geranylgeranyltransferase Subunit Alpha) is a Protein Coding gene. Diseases associated with RABGGTA include Choroideremia. Among its related pathways are Gene Expression and Signaling events mediated by PRL. Gene Ontology (GO) annotations related to this gene include Rab GTPase binding and protein prenyltransferase activity.

Function:

Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to both cysteines in Rab proteins with an -XXCC, -XCXC and -CCXX C-terminal, such as RAB1A, RAB3A and RAB5A respectively.

Similarity:

Belongs to the protein prenyltransferase subunit alpha family.

Contains 5 LRR (leucine-rich) repeats.

Contains 6 PFTA repeats.

SWISS:

Q92696

Gene ID:

5875

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

产品图片