产品货号 :  mlR7584

英文名称 :  Bcl 2 like 13 protein

中文名称 :  Bcl2样凋亡蛋白13抗体

别    名 :  Apoptosis facilitator; Bcl 2 like 13; Bcl 2 like 13 protein; BCL2 like 13 apoptosis facilitator; BCL2 like 13; Bcl2 like 13 protein; BCL2L13; MIL 1; MIL1; MIL1 protein; Protein Mil1; B2L13_HUMAN.  

研究领域 :  细胞生物  细胞凋亡  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应  :  Human, Mouse, Chicken, Dog, Pig, Horse, Rabbit,

产品应用 :  WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 （石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  53kDa

细胞定位 :  细胞核 细胞浆 细胞膜

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human Bcl rambo/Bcl 2 like 13 protein:281-380/485

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍 :   Bcl rambo shares common structural characteristics with other members of the anti-apoptotic Bcl2 family members, but differs from them at its C-terminus, where a 250 amino acid sequence preceeds the membrane anchor region. It also differs from other pro-apoptotic Bcl-2 family members in that its membrane anchor C-terminus region is responsible for its apoptotic activity, not its Bcl-2 homology motifs. Bcl rambo may promote the activation of caspase-3 and apoptosis.

Function:

May promote the activation of caspase-3 and apoptosis.

Subunit:

Monomer

Subcellular Location:

Isoform 2: Mitochondrion membrane; Single-pass membrane protein (Potential). Nucleus.

Isoform 1: Nucleus

Tissue Specificity:

Ubiquitous, with the highest levels of expression in heart, placenta and pancreas.

Similarity:

Belongs to the Bcl-2 family.

SWISS:

Q9BXK5

Gene ID:

23786

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

产品图片