产品货号 :  mlR21289

英文名称 :  RBM15B

中文名称 :  RNA结合蛋白15B抗体

别    名 :  1810017N16Rik; Chromosome 3p21.1 gene sequence; HUMAGCGB; huOTT3; One twenty two protein 3; One-twenty two protein 3; OTT3; Putative RNA binding protein 15B; Putative RNA-binding protein 15B; RB15B_HUMAN; RBM15B; RGD1305937; RNA binding motif protein 15B; RNA-binding motif protein 15B.  

研究领域 :  细胞生物  信号转导  结合蛋白  表观遗传学  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应  :  Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep,

产品应用 :  ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  97kDa

细胞定位 :  细胞核

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human RBM15B:581-680/890

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍 :   Members of the SPEN (Split-end) family of proteins, including RBM15B, have repressor function in several signaling pathways and may bind to RNA through interaction with spliceosome components (Hiriart et al., 2005 [PubMed 16129689]).[supplied by OMIM, Feb 2009]

Function:

May function in the regulation of alternative or illicit splicing.

Subcellular Location:

Nucleus > nucleoplasm. Colocalizes with BMLF1 in the nucleus. Localized in the nucleoplasm with a granular staining pattern and excluded from the nucleoli.

Tissue Specificity:

Ubiquitously expressed.

Similarity:

Belongs to the RRM Spen family.

Contains 3 RRM (RNA recognition motif) domains.

Contains 1 SPOC domain.

SWISS:

Q8NDT2

Gene ID:

109095

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

产品图片