产品货号 :  mlR12764

英文名称 :  PNPLA8

中文名称 :  磷脂酶patatin样域包含蛋白8抗体

别    名 :  Calcium-independent phospholipase A2-gamma; Intracellular membrane associated calcium independent phospholipase A2 gamma; Intracellular membrane-associated calcium-independent phospholipase A2 gamma; IPLA2 2; iPLA2 gamma; IPLA2(GAMMA); iPLA2-2; iPLA2-gamma; IPLA22; IPLA2G; Patatin like phospholipase domain containing protein 8; Patatin-like phospholipase domain-containing protein 8; PLPL8_HUMAN; PNPLA-gamma; PNPLA8.  

研究领域 :  肿瘤  心血管  细胞生物  信号转导  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应 :  Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, Guinea Pig,

产品应用 :  ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  88kDa

细胞定位 :  细胞浆

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human PNPLA8:601-700/782

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍 :  This gene encodes a member of the patatin-like phospholipase domain containing protein family. Members of this family are phospholipases which catalyze the cleavage of fatty acids from membrane phospholipids. The product of this gene is a calcium-independent phospholipase. A pseudogene of this gene is located on the X chromosome. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]

Function:

Calcium-independent phospholipase A2, which catalyzes the hydrolysis of the sn-2 position of glycerophospholipids, PtdSer and to a lower extent PtdCho. Cleaves membrane phospholipids.

Subcellular Location:

Endoplasmic reticulum membrane. Golgi apparatus membrane. Cytoplasm > perinuclear region.

Tissue Specificity:

Expressed in parenchymal tissues including heart, skeletal muscle, placenta, brain, liver and pancreas. Also expressed in bronchial epithelial cells and kidney. Highest expression is observed in skeletal muscle and heart.

Similarity:

Contains 1 patatin domain.

SWISS:

Q9NP80

Gene ID:

50604

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.