产品货号 :  mlR12610

英文名称 :  PEBP4

中文名称 :  磷脂酰乙醇胺结合蛋白4抗体

别    名 :  1700051A02Rik; 1700081D17Rik; AI429082; CORK 1; CORK1; Cousin of RKIP 1 protein; GWTM1933; hPEBP4; MGC22776; PEBP 4; Phosphatidylethanolamine binding protein 4; PRO4408; Protein cousin of RKIP 1; UNQ1933/PRO4408.  

研究领域 :  肿瘤  细胞生物  细胞凋亡  激酶和磷酸酶  结合蛋白  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应 :  Human,

产品应用 :  ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  26kDa

细胞定位 :  细胞浆

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human PEBP4:151-227/227

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍 :  The phosphatidylethanolamine (PE)-binding proteins, including PEBP4, are an evolutionarily conserved family of proteins with pivotal biologic functions, such as lipid binding and inhibition of serine proteases (Wang et al., 2004 [PubMed 15302887]).[supplied by OMIM, Dec 2008]

Function:

Seems to promote cellular resistance to TNF-induced apoptosis by inhibiting activation of the Raf-1/MEK/ERK pathway, JNK and phosphatidylethanolamine externalization

Subcellular Location:

Lysosome

Tissue Specificity:

Ubiquitously expressed. Highly expressed in tumor cells.

Similarity:

Belongs to the phosphatidylethanolamine-binding protein family.

SWISS:

Q96S96

Gene ID:

157310

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.