产品货号 : mlR12362
英文名称 : Fibromodulin
中文名称 : 纤维调节蛋白抗体
别 名 : Collagen binding 59 kDa protein; Collagen-binding 59 kDa protein; Fibromodulin; Fibromodulin precursor; Fibromodulin proteoglycan; FM; FMOD; FMOD_HUMAN; Keratan sulfate proteoglycan fibromodulin; KSPG fibromodulin; SLRR2E.
研究领域 : 细胞生物 发育生物学 信号转导 干细胞
抗体来源 : Rabbit
克隆类型 : Polyclonal
交叉反应 : Human, Mouse, Rat, Sheep,
产品应用 : ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 : 41kDa
细胞定位 : 细胞外基质 分泌型蛋白
性 状 : Lyophilized or Liquid
浓 度 : 1mg/ml
免 疫 原 : KLH conjugated synthetic peptide derived from human Fibromodulin:121-180/376
亚 型 : IgG
纯化方法 : affinity purified by Protein A
储 存 液 : 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 : Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed : PubMed
产品介绍 : Fibromodulin is a ubiquitous protein that is most prominent in articular cartilage, tendon, and ligament. The human Fibromodulin gene maps to chromosome 1q32 and encodes a 376 amino acid protein.
Function:
Affects the rate of fibrils formation. May have a primary role in collagen fibrillogenesis.
Subunit:
Binds to type I and type II collagen (By similarity).
Subcellular Location:
Secreted, extracellular space, extracellular matrix.
Post-translational modifications:
Binds keratan sulfate chains.
Similarity:
Belongs to the small leucine-rich proteoglycan (SLRP) family.
SLRP class II subfamily.
Contains 11 LRR (leucine-rich) repeats.
Contains 1 LRRNT domain.
SWISS:
Q06828
Gene ID:
2331
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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