产品货号 :  mlR18555

英文名称 :  ZCCHC6

中文名称 :  ZCCHC6蛋白抗体

别  名 :  KIAA1711; MGC38585; PAP associated domain containing 6; PAPD6; Zinc finger CCHC domain containing 6.  

研究领域 :  转录调节因子  锌指蛋白  表观遗传学  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应 :   Human, Mouse, Rat, Dog, Pig, Rabbit,

产品应用 :  WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  171kDa

细胞定位 :  细胞核 细胞浆

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human ZCCHC6:111-210/1495

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍 :  ZCCHC6 is a 1,495 amino acid uridylyltransferase that mediates RNA uridylation. A member of the DNA polymerase type-B-like family, ZCCHC6 contains three CCHC-type zinc fingers and two PAP-associated domains, and exists as six alternatively spliced isoforms. The gene encoding ZCCHC6 maps to human chromosome 9q21.33 and mouse chromosome 13 B2.

Function:

Uridylyltransferase that mediates the terminal uridylation of some specific RNAs. Not involved in uridylation of precursor let-7 (pre-let-7) miRNA. Does not play a role in replication-dependent histone mRNA degradation.

Similarity:

Belongs to the DNA polymerase type-B-like family.

Contains 3 CCHC-type zinc fingers.

Contains 2 PAP-associated domains.

SWISS:

Q5VYS8

Gene ID:

79670

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

产品图片