产品货号 : mlR16755
英文名称 : KLF16
中文名称 : 多巴胺受体调节因子DRRF抗体
别 名 : AI843742; Basic transcription element binding protein 4; Basic transcription element-binding protein 4; BTE binding protein 4; BTE-binding protein 4; BTEB 4; BTEB4; Dopamine receptor regulating factor; DRRF; KLF 16; Klf16; KLF16_HUMAN; Krueppel-like factor 16; Kruppel like factor 16; Likely ortholog of mouse dopamine receptor regulating factor; MGC187751; Novel Sp1 like zinc finger transcription factor 2; Novel Sp1-like zinc finger transcription factor 2; NSLP 2; NSLP2; RCG29340; Transcription factor BTEB 4; Transcription factor BTEB4; Transcription factor NSLP 2; Transcription factor NSLP2.
研究领域 : 神经生物学 转录调节因子 锌指蛋白 表观遗传学
抗体来源 : Rabbit
克隆类型 : Polyclonal
交叉反应 : Human, Mouse, Rat, Pig, Cow,
产品应用 : WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 : 26kDa
细胞定位 : 细胞核
性 状 : Lyophilized or Liquid
浓 度 : 1mg/ml
免 疫 原 : KLH conjugated synthetic peptide derived from human KLF16:101-200/252
亚 型 : IgG
纯化方法 : affinity purified by Protein A
储 存 液 : 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 : Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed : PubMed
产品介绍background:
KLF16 is a 252 amino acid protein that contains three C2H2-type zinc fingers and belongs to the KLF transcription factor family. Localized to the nucleus and expressed at high levels in brain , KLF16 functions as a transcription factor that binds specifically to GT and GC boxes, displacing the transcription factors Sp1 and Sp3 and effectively modulating dopaminergic transmission in the brain.
Function:
Transcription factor that binds GC and GT boxes and displaces Sp1 and Sp3 from these sequences. Modulates dopaminergic transmission in the brain.
Subcellular Location:
Nucleus.
Similarity:
Belongs to the Sp1 C2H2-type zinc-finger protein family.
Contains 3 C2H2-type zinc fingers.
SWISS:
Q9BXK1
Gene ID:
83855
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.