产品货号 :  mlR17288

英文名称 :  SCMH1

中文名称 :  多梳蛋白SCMH1抗体

别    名 :  Polycomb protein SCMH1; SCMH 1; SCMH1; SCMH1_HUMAN; Scml 3; Scml3; Sex comb on midleg 1; Sex comb on midleg homolog 1.  

研究领域 :  细胞生物  转录调节因子  表观遗传学  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应 :  Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep,

产品应用 :  ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  73kDa

细胞定位 :  细胞核

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human SCMH1:1-100/660

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍 Component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.

Subcellular Location:

Nucleus.

Tissue Specificity:

Strongly expressed in heart, muscle and pancreas. Weakly expressed in brain, placenta, lung, liver and kidney.

Similarity:

Belongs to the SCM family.

Contains 2 MBT repeats.

Contains 1 SAM (sterile alpha motif) domain.

SWISS:

Q96GD3

Gene ID:

22955

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.