产品货号 : mlR17774
英文名称 : MRPL18
中文名称 : 线粒体核糖体蛋白L18抗体
别 名 : 39S ribosomal protein L18; 39S ribosomal protein L18 mitochondrial; 39S ribosomal protein L18, mitochondrial precursor; HSPC071; L18mt; Mitochondrial ribosomal protein L18; Mitochondrial ribosomal protein L18 (MRPL18 protein); MRP-L18; Mrpl18; RM18_HUMAN; RP1 195P10.3 001.
研究领域 : 细胞生物 转录调节因子 线粒体 表观遗传学
抗体来源 : Rabbit
克隆类型 : Polyclonal
交叉反应 : Human, Mouse, Rat, Chicken, Dog, Horse, Rabbit,
产品应用 : ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user
分 子 量 : 21kDa
细胞定位 : 细胞浆 线粒体
性 状 : Lyophilized or Liqui
浓 度 : 1mg/ml
免 疫 原 : KLH conjugated synthetic peptide derived from human MRPL18:61-160/180
亚 型 : IgG
纯化方法 : affinity purified by Protein A
储 存 液 : 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 : Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed : PubMed
产品介绍 : Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the L18P ribosomal protein family. Three polymorphic sites exist in this gene, one of which is three nt in length which causes an extra aa near the N-terminus. [provided by RefSeq, Jul 2008]
Function:
Belongs to the ribosomal protein L18P family.
Subcellular Location:
Mitochondrion.
Similarity:
Belongs to the ribosomal protein L18P family.
SWISS:
Q9H0U6
Gene ID:
29074
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.