产品货号 :  mlR18140

英文名称 :  IGSF22

中文名称 :  免疫球蛋白超家族成员22抗体

别    名 :  Immunoglobulin superfamily member 22.  

研究领域 :  细胞生物  免疫学  细胞膜受体  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应 :  Human, Dog, Cat,

产品应用 :  ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  100kDa

细胞定位 :  细胞膜

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human IGSF22:221-320/903

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍 :  IGSF22 (immunoglobulin superfamily member 22) is a 903 amino acid protein that contains two fibronectin type-III domains and four Ig-like (immunoglobulin-like) domains, and is a member of the immunoglobulin superfamily. Members of this family of proteins usually localize to the cell membrane, and may act as receptors in immune response pathways. The gene encoding IGSF22 maps to human chromosome 11p15.1. Chromosome 11 houses over 1,400 genes, comprises nearly 4% of human genomic DNA and is considered a gene and disease association dense chromosome. The blood disorders Sickle cell anemia and thalassemia are caused by HBB gene mutations, while Wilms' tumors, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11-encoded genes.

Similarity:

Contains 2 fibronectin type-III domains.

Contains 4 Ig-like (immunoglobulin-like) domains.

SWISS:

Q8N9C0

Gene ID:

283284

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.