产品货号 :  mlR12760

英文名称 :  VOPP1

中文名称 :  EGFR扩增和过度表达蛋白抗体

别    名 :  ECop; EGFR-coamplified and overexpressed protein; GASP; Glioblastoma-amplified secreted protein; overexpressed in cancer; prosurvival protein 1; Putative NF-kappa-B-activating protein 055N; Vesicular; Vesicular, overexpressed in cancer, prosurvival protein 1; vopp1; VOPP1_HUMAN.  

研究领域 :  肿瘤  细胞生物  细胞凋亡  转录调节因子  表观遗传学  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应 :  Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep,

产品应用 :  ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  17kDa

细胞定位 :  细胞浆

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human VOPP1:41-140/172 <Cytoplasmic>

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍 :  VOPP1 (Vesicular, Overexpressed In Cancer, Prosurvival Protein 1) is a Protein Coding gene. GO annotations related to this gene include signal transducer activity.

Function:

Increases the transcriptional activity of NFKB1 by facilitating its nuclear translocation, DNA-binding and associated apoptotic response, when overexpressed.

Subcellular Location:

Cytoplasmic vesicle membrane. When overexpressed, localizes in the nucleus and perinuclear regions.

Tissue Specificity:

Widely expressed with highest levels in thymus and ovary.

Similarity:

Belongs to the VOPP1/ECOP family.

SWISS:

Q96AW1

Gene ID:

81552

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.