产品货号 :  mlR17816

英文名称 :  MRPS18B

中文名称 :  线粒体核糖体蛋白S18B抗体

别    名 :  28S ribosomal protein S18-2; 28S ribosomal protein S18b; 28S ribosomal protein S18b, mitochondrial; C6orf14; DKFZp564H0223; HSPC 183; HSPC183; mitochondrial; Mitochondrial ribosomal protein S18 2; Mitochondrial ribosomal protein S18B; MRP S18 2; MRP S18 b; MRP S18b; MRP-S18-2; MRP-S18-b; MRPS 18B; MRPS18 2; Mrps18-b; MRPS18B; PTD017; RT18B_HUMAN; S18amt; S18mt-b.  

研究领域 :  细胞生物  转录调节因子  细胞类型标志物  线粒体  表观遗传学  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应 :  Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep, Cat,

产品应用 :  ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user. 

分 子 量 :  29kDa

细胞定位 :  细胞浆 线粒体

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml 

免 疫 原 :  KLH conjugated synthetic peptide derived from human MRPS18B:41-140/258

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A 

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 

PubMed :  PubMed

产品介绍 :  Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S18P family. The encoded protein is one of three that has significant sequence similarity to bacterial S18 proteins. The primary sequences of the three human mitochondrial S18 proteins are no more closely related to each other than they are to the prokaryotic S18 proteins. Pseudogenes corresponding to this gene are found on chromosomes 1q and 2q. [provided by RefSeq, Jul 2008]

Subunit:

Component of the mitochondrial ribosome small subunit (28S) which comprises a 12S rRNA and about 30 distinct proteins. 

Subcellular Location:

Mitochondrion.

Similarity:

Belongs to the ribosomal protein S18P family.

SWISS:

Q9Y676

Gene ID:

28973 

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.