产品货号 :  mlR14662

英文名称 :  EXOC6

中文名称 :  EXOC6蛋白抗体

别    名 :  DKFZp761I2124; EXOC 6; EXOC6A; Exocyst complex component 6; Exocyst complex component Sec15A; FLJ1125; FLJ11251; MGC33397; SEC15; SEC15 like 1; SEC15 like protein 1; SEC15 like protein 3; SEC15A; EXOC6_HUMAN; SEC15L; SEC15L1; SEC15L3; Sec15p.  

研究领域 :  细胞生物  信号转导  转录调节因子  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应 :   Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,

产品应用 :  ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  94kDa

细胞定位 :  细胞浆 细胞膜

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human EXOC6:711-804/804

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍  :  The product of this gene belongs to the SEC15 family. It is highly similar to the protein encoded by Saccharomyces cerevisiae SEC15 gene. This protein is essential for vesicular traffic from the Golgi apparatus to the cell surface in yeast. It is one of the components of a multiprotein complex required for exocytosis. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

Function:

EXOC6 is a component of the exocyst complex involved in the docking of exocystic vesicles with fusion sites on the plasma membrane.

Subunit:

The exocyst complex is composed of EXOC1, EXOC2, EXOC3, EXOC4, EXOC5, EXOC6, EXOC7 and EXOC8. Interacts with CNTRL. Interacts with RAB11A in a GTP-dependent manner (By similarity).

Similarity:

Belongs to the SEC15 family.

SWISS:

Q8TAG9

Gene ID:

54536

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

产品图片