产品货号 :  mlR17579

英文名称 :  OXSM

中文名称 :  β-酮脂酰合成酶/β-ketoacyl synthase抗体

别    名 :  3 oxoacyl ACP synthase, mitochondrial; 3 oxoacyl acyl carrier protein synthase; 3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial; Acyl malonyl acyl carrier protein condensing enzyme; Beta ketoacyl ACP synthase; beta-ketoacyl synthase; beta-ketoacyl synthase, mitochondrial; Beta-ketoacyl-ACP synthase; C80494; FASN2D; FLJ20604; KASI; KS; OXSM; OXSM_HUMAN; type II mitochondrial beta ketoacyl synthase.  

研究领域 :  肿瘤  细胞生物  信号转导  新陈代谢  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应 :  Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Guinea Pig,

产品应用 :  ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  49kDa

细胞定位 :  细胞浆

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human OXSM:261-360/459

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍 :  This gene encodes a beta-ketoacyl synthetase. The encoded enzyme is required for elongation of fatty acid chains in the mitochondria. Alternatively spliced transcript variants have been described.[provided by RefSeq, Feb 2009]

Function:

May play a role in the biosynthesis of lipoic acid as well as longer chain fatty acids required for optimal mitochondrial function.

Subcellular Location:

Mitochondrion.

Tissue Specificity:

Widely expressed. Higher expression in heart, skeletal muscle, liver and kidney which contain high levels of active mitochondria.

Similarity:

Belongs to the beta-ketoacyl-ACP synthases family.

SWISS:

Q9NWU1

Gene ID:

54995

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.