产品货号 :  mlR16008

英文名称 :  FAM5C

中文名称 :  FAM5C蛋白抗体

别    名 :  B830045N13Rik; BMP/retinoic acid inducible neural specific protein 3; BRINP3; BRNP3_HUMAN; DBCCR1 like protein 1; DBCCR1L; DBCCR1L1; Family with sequence similarity 5, member C; MGC107461; MGC40674; OTTMUSP00000028549; Protein FAM5C; RP11-445K1.1; RP23-212I24.1.  

研究领域 :  细胞生物  交换蛋白  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应 :   Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit, Sheep,

产品应用 :  ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  85kDa

细胞定位 :  细胞浆

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human FAM5C:681-766/766

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍 :   FAM5C belongs to the FAM5 family.

Function:

Inhibits neuronal cell proliferation by negative regulation of the cell cycle transition. Promotes pituitary gonadotrope cell proliferation, migration and invasion, when overexpressed. May play a role in cell pituitary tumor development.

Subcellular Location:

Secreted

Tissue Specificity:

Strongly expressed in oral keratinocytes compared to the weak expression in tongue squamous cell carcinoma (SCC). Expressed in endothelial and aortic smooth muscle cells. Overexpressed in gonadotropinomas compared to normal pituitarie tissues.

Similarity:

Belongs to the BRINP family.

Contains 1 MACPF domain.

SWISS:

Q76B58

Gene ID:

339479

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

产品图片