产品货号 : mlR6867
英文名称 : NLRP9
中文名称 : 富含亮氨酸重复结构域蛋白9抗体
别 名 : LRR and PYD domains-containing protein 9; NACHT; NACHT, LRR and PYD domains-containing protein 9; NALP9_HUMAN; NLRP9; Nucleotide-binding oligomerization domain protein 6; PYRIN and NACHT-containing protein 12.
研究领域 : 细胞生物 免疫学 细胞凋亡 转录调节因子
抗体来源 : Rabbit
克隆类型 : Polyclonal
交叉反应 : Human, Mouse, Rat,
产品应用 : WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 : 109kDa
细胞定位 : 细胞浆
性 状 : Lyophilized or Liquid
浓 度 : 1mg/ml
免 疫 原 : KLH conjugated synthetic peptide derived from human NLRP9:701-800/991
亚 型 : IgG
纯化方法 : affinity purified by Protein A
储 存 液 : 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 : Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed : PubMed
产品介绍 : The protein encoded by this gene belongs to the NALP protein family. Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). This protein may play a regulatory role in the innate immune system as similar family members belong to the signal-induced multiprotein complex, the inflammasome, that activates the pro-inflammatory caspases, caspase-1 and caspase-5. [provided by RefSeq, Jul 2008].
Function:
Involved in inflammation (Potential).
Subcellular Location:
Cytoplasm.
Similarity:
Belongs to the NLRP family.
Contains 1 DAPIN domain.
Contains 6 LRR (leucine-rich) repeats.
Contains 1 NACHT domain.
SWISS:
Q7RTR0
Gene ID:
338321
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品图片