产品货号 :  mlR3801

英文名称 :  Lambda Light Chain

中文名称 :  λ轻链抗体

别    名 :  Ig lambda chain C regions; Bence Jones protein; BJP; Constant region of lambda light chains; IGLC 1; IGLC 2; IGLC 3; IGLC; IGLC1; IGLC2; IGLC3; LAC1_HUMAN; Immunoglobulin lambda constant 1; Mcg marker; Paraprotein; Ig lambda-1 chain C regions.  

研究领域 :  肿瘤  细胞生物  免疫学  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应  :  Human, Mouse, Rat,

产品应用 :  WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  22.5kDa

细胞定位 :  分泌型蛋白

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human Lambda Light Chain:41-106/106

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍 :   All five immunoglobulin classes share the same basic four polypeptide chain structure of two heavy-chains and two light chains. There are five heavy chain types, and two light-chain types (Kappa and Lambda) both having a molecular weight of 22.5kDa. Any heavy-chain type can associate with either light-chain type, but on any immunoglobulin molecule both light-chains are of the same type. Kappa and Lambda consist of a variable region and a constant region and can easily be differentiated by the antigenic properties of the constant region.

Subcellular Location:

Cytoplasmic

Similarity:

Contains 1 Ig-like (immunoglobulin-like) domain.

SWISS:

P01701

Gene ID:

3535

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

该抗体特异识别免疫球蛋白λ轻链，可用于鉴定白血病、浆细胞瘤以及某些非霍奇金氏淋巴瘤。这些肿瘤的共同特征是只限于单个轻链的表达，因此轻链Kappa和Lamda可用于良恶性淋巴病变（反应性淋巴细胞增生和淋巴瘤）的辅助性诊断。