产品货号 :  mlR12651

英文名称 :  SNAPC5

中文名称 :  小核RNA激活复合多肽SNAPC5抗体

别    名 :  Small nuclear RNA activating complex polypeptide 5 19kDa; Small nuclear RNA activating complex polypeptide 5; SNAP 19; SNAP19; SNAPc 19 kDa subunit; SNAPC 5; SNAPc subunit 5; snRNA activating protein complex 19 kDa subunit; snRNA activating protein complex subunit 5.  

研究领域 :  细胞生物  信号转导  转录调节因子  表观遗传学  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应 :  Human, Mouse, Rat, Chicken, Pig, Cow, Rabbit, Sheep,

产品应用 :  ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  11kDa

细胞定位 :  细胞核

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human SNAPC5:1-50/98

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍 :  SNAPC5 is a subunit of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. SNAPC5 binds to the proximal sequence element (PSE) common to the promotor regions of these 2 types of genes, and recruits TBP and BRF2 to the U6 snRNA TATA box. 

Function:

Part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. Binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes. Recruits TBP and BRF2 to the U6 snRNA TATA box. 

Subunit:

Part of the SNAPc complex composed of 5 subunits: SNAPC1, SNAPC2, SNAPC3, SNAPC4 and SNAPC5. SNAPC5 interacts with SNAPC4.1 Publication. 

Subcellular Location:

Nuclear. 

SWISS:

O75971 

Gene ID:

10302

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.