产品货号 :  mlR14061

英文名称 :  CRISP11

中文名称 :  富含半胱氨酸分泌蛋白11抗体

别    名 :  CRISP-11; CRISPLD2; CRISP11; Crispld2; CRLD2_HUMAN; Cysteine-rich secretory protein 11; Cysteine-rich secretory protein LCCL domain-containing 2; DKFZP434B044; LCCL domain-containing cysteine-rich secretory protein 2; LCRISP2; LCRISP2; MGC74865.  

研究领域 :  细胞生物  信号转导  转录调节因子  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应 :   Human, Mouse, Rat, Dog, Pig, Cow, Sheep,

产品应用 :  WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  54kDa

细胞定位 :  细胞浆

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human CRISP11:101-200/497

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍 :   Cysteine-rich secretory proteins (CRISPs) represent a family of evolutionarily conserved proteins that may play a role in the innate immune system and are transcriptionally regulated by androgens in several tissues. CRISP proteins are highly expressed in the mammalian reproductive tract and in the venom secretory ducts of some reptiles. CRISP-11 (cysteine-rich secretory protein 11), also known as cysteine-rich secretory protein LCCL domain-containing 2 (CRISPLD2 or LCRISP2), is a 497 amino acid protein containing 2 LCCL domains, which are thought to function as autonomous folding domains used to construct modular proteins through exon shuffling. Serum concentrations of CRISP-11 have been shown to be an indicator of a patient’s exposure to lipopolysaccahride (LPS), the immunostimulatory component of Gram-negative bacteria, and can determine one’s sensitivity to it.

Function:

Promotes matrix assembly.

Subcellular Location:

Secreted.

Similarity:

Belongs to the CRISP family.

Contains 2 LCCL domains.

SWISS:

Q9H0B8

Gene ID:

83716

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

产品图片