产品货号 : mlR16747
英文名称 : KK-LC-1/CT83
中文名称 : 癌/睾丸抗原83抗体
别 名 : Cancer/testis antigen 83; Chromosome X open reading frame 61; CT83; CXorf61; Kita-kyushu lung cancer antigen 1; KK-LC-1; KKLC1; KKLC1_HUMAN.
研究领域 : 肿瘤 细胞生物 免疫学 肿瘤细胞生物标志物
抗体来源 : Rabbit
克隆类型 : Polyclonal
交叉反应 : Human,
产品应用 : ELISA=1:500-1000 IHC-P=1:400-800 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 : 13kDa
细胞定位 : 细胞膜
性 状 : Lyophilized or Liquid
浓 度 : 1mg/ml
免 疫 原 : KLH conjugated synthetic peptide derived from human KK-LC-1/CT83:51-113/113 <Extracellular>
亚 型 : IgG
纯化方法 : affinity purified by Protein A
储 存 液 : 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 : Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMedPubMed
产品介绍background:
The X and Y chromosomes are the human sex chromosomes. Chromosome X consists of about 153 million base pairs and nearly 1,000 genes. The combination of an X and Y chromosome lead to normal male development while two copies of X lead to normal female development. There are a number of conditions related to an unsual number and combination of sex chromosomes being inherited. More than one copy of the X chromosome with a Y chromosome causes Klinefelter's syndrome. A single copy of X alone leads to Turner's syndrome. More than 2 copies of the X chromosome, in the absence of a Y chromosome, is known as Triple X syndrome. Color blindness, hemophilia, and Duchenne muscular dystrophy are well known X chromosome-linked conditions which affect males more frequently as males carry a single X chromosome. The KK-LC-1 gene product has been provisionally designated KK-LC-1 pending further characterization.
Function:
Specifically expressed in testis. Expressed by cancer cell lines.
Subcellular Location:
Cell membrane.
SWISS:
Q5H943
Gene ID:
203413
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.