产品货号 :  mlR19684

英文名称 :  SFRS14

中文名称 :  富含精氨酸/丝氨酸剪接因子14抗体

别    名 :  Arginine/serine rich splicing factor 14; arginine/serine-rich 14; Arginine/serine-rich-splicing factor 14; DKFZp779L2418; KIAA0365; Splicing factor; Splicing factor, arginine/serine-rich 14; Sugp2; SUGP2_HUMAN; SURP and G-patch domain-containing protein 2.  

研究领域 :  细胞生物  表观遗传学  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应 :  Human, Mouse, Rat,

产品应用 :  WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  120kDa

细胞定位 :  细胞核

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human SFRS14:751-850/1082

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍 :  This gene encodes a member of the arginine/serine-rich family of splicing factors. The encoded protein functions in mRNA processing. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2009]

Function:

May play a role in mRNA splicing.

Subunit:

Interacts with MYOD1 (By similarity). Component of the SLC (SFMBT1-LSD1-CoREST) corepressor complex, which also contains KDM1A/LSD1 and RCOR1/CoREST. Interacts with KDM1A/LSD1 and RCOR1/CoREST.

Subcellular Location:

Nucleus.

Tissue Specificity:

Detected in adult testis, and in fetal brain and kidney.

Similarity:

Contains 1 G-patch domain.

Contains 2 SURP motif repeats.

SWISS:

Q8IX01

Gene ID:

10147

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.