产品货号 :  mlR4041

英文名称 :  Transaldolase 1

中文名称 :  转醛醇酶/EPS8L2抗体

别    名 :  Dihydroxyacetone transferase; EPS8L2; Glycerone transferase; TAL; TAL H; TALDO; TALDO1; TALDOR; TALH; Transaldolase 1; Transaldolase1; Transaldolase-1; EC 2.2.1.2; TALDO_HUMAN.  

研究领域 :  肿瘤  细胞生物  免疫学  神经生物学  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应 :   Human, Mouse, Rat, Dog, Cow, Horse, Sheep,

产品应用 :  WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  37kDa

细胞定位 :  细胞浆

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human Transaldolase 1:145-250/337

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍 :   Transaldolase 1 is a key enzyme of the nonoxidative pentose phosphate pathway providing ribose-5-phosphate for nucleic acid synthesis and NADPH for lipid biosynthesis. This pathway can also maintain glutathione at a reduced state and thus protect sulfhydryl groups and cellular integrity from oxygen radicals. The functional gene of transaldolase 1 is located on chromosome 11 and a pseudogene is identified on chromosome 1 but there are conflicting map locations. The second and third exon of this gene were developed by insertion of a retrotransposable element. This gene is thought to be involved in multiple sclerosis.

Function:

Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

Subunit:

Homodimer.

DISEASE:

Transaldolase 1 deficiency (TALDO1 deficiency) [MIM:606003]: Results in telangiectases of the skin, hepatosplenomegaly, and enlarged clitoris. Note=The disease is caused by mutations affecting the gene represented in this entry.

SWISS:

Q9H6S3

Gene ID:

64787

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Transaldolase 1称醛羧移转酶 或转二羟丙酮基酶，经研究该蛋白与多发性硬化症有关。