产品货号 :  mlR23427 

英文名称 :  Salusin alpha 

中文名称 :  心血管调节肽Salusin-α抗体 

别    名 :  Prosalusin precursor; TOR2A; TORP1; Torsin 2A [Precursor]; Torsin family 2 member A; Torsin related protein 1; TOR2A_HUMAN.   

研究领域 :  心血管  免疫学  神经生物学   

抗体来源 :  Rabbit 

克隆类型 :  Polyclonal 

交叉反应 :   Human,

产品应用 :  WB=1:500-2000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user. 

分 子 量 :  33kDa

细胞定位 :  分泌型蛋白

性    状 :  Lyophilized or Liquid 

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human Salusin alpha:181-242/242 

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A 

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed 

产品介绍 :   Salusins are multifunctional bioactive peptides discovered by bioinformatics analyses of a full-length cDNA library. Salusin alpha and salusin beta are related peptides of 28 and 20 amino acids that were recently characterized. These peptides are considered to be biosynthesized from preprosalusin, an alternative-splicing product of the torsion dystonia-related gene (TOR2A), after frameshift reading and digestion at dibasic amino acids. Salusin alpha has recently been shown to be involved in atherosclerosis; it potently suppresses acyl-CoA:cholesterol acyltransferase-1 which stores cholesterol ester converted from free cholesterol in macrophages, thereby reducing human macrophage foam cell formation. 

Subcellular Location:

Secreted.

Tissue Specificity:

Isoform 1 is expressed ubiquitously, except in cardiac and endothelial tissues. 

Similarity:

Belongs to the clpA/clpB family. Torsin subfamily. 

SWISS:

Q5JU69 

Gene ID:

27433

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

产品图片