产品货号 :  mlR8040

英文名称 :  GNL1

中文名称 :  鸟嘌呤核苷酸结合蛋白1抗体

别  名 :  Gnl1; GNL1_HUMAN; GTP binding protein HSR1; GTP-binding protein HSR1; Guanine nucleotide binding protein like 1; Guanine nucleotide-binding protein-like 1; HSR1; HSR1 GTP binding protein.  

研究领域 :  细胞生物  免疫学  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应 :   Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, Monkey, y

产品应用 :  WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 （石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  69kDa

细胞定位 :  细胞核 细胞外基质 分泌型蛋白

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human GNL1:301-400/607

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍 :   The GNL1 gene, identified in the human major histocompatibility complex class I region, shows a high degree of similarity with its mouse counterpart. The GNL1 gene is located less than 2 kb centromeric to HLA-E, in the same transcriptional orientation. GNL1 is telomeric to HLA-B and HLA-C. [provided by RefSeq, Jul 2008].

Function:

Possible regulatory or functional link with the histocompatibility cluster.

Post-translational modifications:

Phosphorylated upon DNA damage, probably by ATM or ATR.

Similarity:

Belongs to the MMR1/HSR1 GTP-binding protein family.

Contains 1 G (guanine nucleotide-binding) domain.

SWISS:

P36915

Gene ID:

2794

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.