产品货号 :  mlR12795

英文名称 :  ZNF185

中文名称 :  锌指蛋白185抗体

别    名 :  LIM domain protein ZNF185; P1 A; P1-A; Zinc finger protein 185 (LIM domain); Zinc finger protein 185; ZN185_HUMAN; ZNF185.  

研究领域 :  肿瘤  细胞生物  锌指蛋白  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应 :  Human, Mouse, Rat, Cow, Horse, Sheep,

产品应用 :  ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  74kDa

细胞定位 :  细胞浆

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human ZNF185:101-200/689

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍  :  Zinc-finger proteins bind nucleic acids and play important roles in various cellular functions, including cell proliferation, differentiation, and apoptosis. This gene encodes a LIM-domain zinc finger protein. The LIM domain is composed of two contiguous zinc finger domains, separated by a two-amino acid residue hydrophobic linker. The LIM domain mediates protein:protein interactions. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq, May 2010]

Function:

May be involved in the regulation of cellular proliferation and/or differentiation. 

Subcellular Location:

Cytoplasm > cytoskeleton. Cell junction > focal adhesion. 

Tissue Specificity:

Expressed in placenta, pancreas and kidney. Also expressed in prostate, testis, ovary and blood. 

Similarity:

Contains 1 LIM zinc-binding domain.

SWISS:

O15231

Gene ID:

7739

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.