产品货号 :  mlR1525

英文名称 :  mucin3/MUC3

中文名称 :  粘蛋白3抗体

别    名 :  Mucin 3; Mucin 3A; Mucin-3A; MUC-3A; Intestinal mucin-3A; Intestinal mucin-3A; intestinal mucin-like; MUC-3A; MUC3; MUC3A; MUC3B; mucin 3, intestinal; mucin 3A, intestinal; MUC3A_HUMAN; mucin 3B, cell surface associated; mucin 3A, cell surface associated.  

研究领域 :  肿瘤  信号转导  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应  :  Human,

产品应用 :  ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  264kDa

细胞定位 :  细胞膜 分泌型蛋白

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human mucin3:1501-1600/1719

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍 :   MUC3 (Mucin 3) is an intestinal glycoprotein distributed in the colon and rectum, and to a lesser extent in breast, lung and salivary tissues. It is involved in conferring mucous visoelasticity.

Function:

Major glycoprotein component of a variety of mucus gels.Thought to provide a protective, lubricating barrier againstparticles and infectious agents at mucosal surfaces. May beinvolved in ligand binding and intracellular signaling.

Subcellular Location:

Isoform 1: Membrane; Single-pass membrane protein.

Isoform 2: Secreted.

Isoform 3: Secreted.

Isoform 4: Secreted.

Isoform 5: Secreted.

Tissue Specificity:

Broad specificity; small intestine, colon,colonic tumors, heart, liver, thymus, prostate, pancreas and gallbladder.

Post-translational modifications:

Highly O-glycosylated and probably also N-glycosylated.

Similarity:

Contains 1 EGF-like domain.

Contains 1 SEA domain.

SWISS:

Q02505

Gene ID:

4584

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.