产品货号 :  mlR2655

英文名称 :  LTB4-R2

中文名称 :  白三烯B4受体2抗体

别    名 :  BLT2R; JULF2; Leukotriene B4 receptor 2; Leukotriene B4 receptor BLT2; LT4R2_HUMAN; LTB4 receptor JULF2; LTB4-R 2; LTB4-R2; LTB4R2; Seven transmembrane receptor BLTR2.  

研究领域 :  肿瘤  心血管  免疫学  信号转导  脂蛋白  新陈代谢  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应 :   Human, Mouse, Rat, Dog, Pig, Cow, Guinea Pig,

产品应用 :  ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  41kDa

细胞定位 :  细胞膜

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human LTB4-R2:25-120/389 <Extracellular>

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍 :   Low-affinity receptor for leukotrienes including leukotriene B4. Mediates chemotaxis of granulocytes and macrophages. The response is mediated via G-proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTB4 > 12-epi-LTB4 > LTB5 > LTB3.

Function:

Low-affinity receptor for leukotrienes including leukotriene B4. Mediates chemotaxis of granulocytes and macrophages. The response is mediated via G-proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTB4 > 12-epi-LTB4 > LTB5 > LTB3.

Subcellular Location:

Cell membrane; Multi-pass membrane protein.

Tissue Specificity:

Widely expressed.

Similarity:

Belongs to the G-protein coupled receptor 1 family.

SWISS:

Q9NPC1

Gene ID:

56413

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

白三烯B4受体2是白三烯B4受体的新亚型，在炎症、免疫系统疾病和变态反应、包括一些肿瘤中发挥着重要作用。