产品货号 :  mlR18462

英文名称 :  ZC3H14

中文名称 :  ZC3H14蛋白抗体

别    名 :  FLJ11806; Mammalian suppressor of tau pathology-2; MGC26892; MSUT-2; Nuclear protein UKp68; NY REN 37; NYREN 37; Renal carcinoma antigen NY REN 37; Renal carcinoma antigen NY-REN-37; Renal carcinoma antigen NYREN 37; suppressor of tau 2, C. elegans, homolog of; SUT2; UKp68; ZC3H14; ZC3HE_HUMAN; Zinc finger CCCH domain-containing protein 14; Zinc finger CCCH type containing 14.  

研究领域 :  细胞生物  结合蛋白  表观遗传学  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应 :  Human,

产品应用 :  ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications
optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  83kDa

细胞定位 :  细胞核 细胞浆

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human ZC3H14:601-700/736

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍  :  ZC3H14 belongs to a family of poly(A)-binding proteins that influence gene expression by regulating mRNA stability, nuclear export, and translation (Kelly et al., 2007 [PubMed 17630287]).[supplied by OMIM, Mar 2010]

Function:

Binds the polyadenosine RNA oligonucleotides.

Subunit:

Interacts with HOOK2.

Subcellular Location:

Cytoplasm and Nucleus speckle.

Post-translational modifications:

Phosphorylated upon DNA damage, probably by ATM or ATR.

Similarity:

Belongs to the ZC3H14 family.

Contains 5 C3H1-type zinc fingers.

SWISS:

Q6PJT7

Gene ID:

79882

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.