产品货号 :  mlR18465

英文名称 :  ZC3H3

中文名称 :  ZC3H3蛋白抗体

别    名 :  KIAA0150; ZC3H3; ZC3H3_HUMAN; ZC3HDC3; Zinc finger CCCH domain containing protein 3; Zinc finger CCCH domain-containing protein 3; Zinc finger CCCH type containing 3; Zinc finger CCCH type domain containing 3.  

研究领域 :  细胞生物  结合蛋白  锌指蛋白  表观遗传学  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应 :   Human, Mouse, Rat, Horse,

产品应用 :  ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  103kDa

细胞定位 :  细胞核

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human ZC3H3:851-948/948

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍 :   ZC3HDC3 is a 948 amino acid protein that contains five C3H1-type zinc finger domains. ZC3HDC3 plays a regulatory role in nuclear adenylation and export. Two isoforms of ZC3H13 exists as a result of alternative splicing events. The gene encoding ZC3H13 maps to chromosome 8, which encodes about 800 genes. Translocation of portions of chromosome 8 with amplifications of the c-Myc gene are found in some leukemias and lymphomas, and typically associated with a poor prognosis. Portions of chromosome 8 have been linked to schizophrenia and bipolar disorder. Trisomy 8, also known as Warkany syndrome 2, most often results in early miscarriage but is occasionally seen in a mosaic form in surviving patients who suffer to a varying degree from a number of symptoms including retarded mental and motor development, and certain facial and developmental defects.

Similarity:

Contains 5 C3H1-type zinc fingers.

SWISS:

Q8IXZ2

Gene ID:

23144

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.