产品货号 :  mlR17660

英文名称 :  Speedy protein C

中文名称 :  快速周期蛋白C抗体

别    名 :  hSpy/Ringo C; Rapid inducer of G2/M progression in oocytes C; Rapid inducer of G2/M progression in oocytes, Xenopus, homolog of, C; RINGO C; Ringo2; SPDYC; SPDYC_HUMAN; speedy C; speedy homolog C; Speedy protein C; Speedy, Xenopus, homolog of, C.  

研究领域 :  细胞生物  细胞周期蛋白  表观遗传学  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应 :  Human,

产品应用 :  ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  33kDa

细胞定位 :  细胞核

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human Speedy protein C:201-293/293

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍 :  Promotes progression through the cell cycle via binding and activation of CDK1 and CDK2.

Function:

Promotes progression through the cell cycle via binding and activation of CDK1 and CDK2. Involved in the spindle-assembly checkpoint. Required for recruitment of MAD2L1, BUBR1 and BUB1 to kinetochores. Required for the correctlocalization of the active form of Aurora B in prometaphase.

Subunit:

Interacts with CDK1 and CDK2. Interacts with AURKB.

Subcellular Location:

Nucleus.

Tissue Specificity:

Expressed in a variety of tissues including bone marrow, kidney, small intestine, liver, placenta and testis.

DISEASE:

Expressed in a variety of tissues including bone marrow, kidney, small intestine, liver, placenta and testis.

Similarity:

Belongs to the Speedy/Ringo family.

SWISS:

Q5MJ68

Gene ID:

387778

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.