产品货号 :  mlR18636

英文名称 :  MAK10

中文名称 :  胚胎生长相关蛋白MAK10抗体

别  名 :  bA379P1.1; Embryonic growth-associated protein homolog; FLJ21613; FLJ22643; N(alpha)-acetyltransferase 35, NatC auxiliary subunit; N-alpha-acetyltransferase 35; N-alpha-acetyltransferase 35, NatC auxiliary subunit; NAA35; NAA35_HUMAN; NatC auxiliary subunit; Protein MAK10 homolog; RP11-379P1.1.  

研究领域 :  细胞生物  免疫学  发育生物学  神经生物学  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应 :  Human, Mouse, Rat, Chicken, Pig, Cow, Horse, Rabbit, Sheep,

产品应用 :  ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  84kDa

细胞定位 :  细胞浆

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human MAK10:151-250/725

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍 :   MAK10 is a 725 amino acid cytoplasmic protein that regulates proliferation of smooth muscle cells. A member of the MAK10 family, MAK10 exists as a component of the N-terminal acetyltransferase C (NatC) complex along with LSmD1 and NAT-12. The gene encoding MAK10 maps to human chromosome 9, which houses over 900 genes and comprises nearly 4% of the human genome. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, and Familial dysautonomia, are both associated with chromosome 9. Notably, chromosome 9 encompasses the largest interferon family gene cluster.

Function:

Regulates proliferation of smooth muscle cells (By similarity). Component of the N-terminal acetyltransferase C (NatC) complex which may catalyze acetylation of N-terminal methionine residues.

Subcellular Location:

Cytoplasm.

Similarity:

Belongs to the MAK10 family.

SWISS:

Q5VZE5

Gene ID:

60560

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.